N152 is an upper division class aimed at Biological Sciences and Neurobiology Majors. It requires Bio93 as a prerequisite. The course is primarily lecture based, and complemented with creative writing assignments as well as review and discussion sessions prior to exams. In this course, the development of the nervous system is discussed in detail with emphasis on the processes that underlie the appearance of complex and highly ordered neural circuits. Molecular, cellular and signaling mechanisms involved in neural induction, specification, migration and death; axon growth, and neural circuit formation are discussed.
The textbook “Development of the Nervous System”, third edition, by Sanes, Reh, and Harris, Elsevier/Academic Press, is recommended for this course but not required. Enrolment in this course is commonly between 120 and 125 students.
Model Organisms, Methods
Neuronal Polarity and Induction
Neurogenesis and Gliogenesis
Neuronal Fate Specification
Neuronal Cell Death
Axon Growth and Guidance
Axon and Dendritic Branching
Synapse Formation and Function
Refinement of Synaptic Connections
Neuroscience in the News