Kristi Clark, PhD
University of Southern California
Title: High resolution mapping of hippocampal development: implications for big data applications
Date: Wednesday, December 12th, 2018
Location: Herklotz Conference Center, Center for Neurobiology of Learning and Memory
In the non-human primate literature, there is evidence to suggest that the hippocampal formation is not fully developed at birth, but gradually develops during childhood, as individual subfields mature and are integrated into existing circuitry. Currently, the same level of detail is not known in humans. Recent technological advances in data acquisition and analytic techniques in neuroimaging make it possible to model the neurodevelopmental trajectory of the human hippocampus at much higher spatial resolution and with greater biological specificity than has ever been possible before. In this seminar, Dr. Clark will discuss her recent work in mapping both the macrostructural and microstructural properties of human hippocampal development and show how these techniques can be applied in the context of big data to develop preliminary methods of MR-based precision medicine.