NEURBIO 206: Molecular Neuroscience is taught Fall Quarter by Professors Mathew Blurton-Jones, Vivek Swarup, and Karina Cramer.
Dr. Mathew Blurton-Jones
Dr. Vivek Swarup
Dr. Karina Cramer
Restriction: Graduate students only. Neurobiology and Behavior Majors only.
Course Objective:
Surveys molecular and cellular mechanisms involved in neuronal function, including control of gene expression, post-transcriptional and post-translational processing, RNA and protein targeting, cell death mechanisms, and molecular genetic basis of neurological disorders. Overview of the molecular aspects of developmental neurobiology.
Sample Syllabus:
| # | Topic |
| 1 | Introduction |
| 2 | Manipulating Gene Expression in the CNS-1 |
| 3 | Manipulating Gene Expression in the CNS-1I |
| 4 | Discussion |
| 5 | Protein-Protein Interactions/Proteomics |
| 6 | Cell Trafficking + Neurologic Disorders |
| 7 | Disease Mechanisms + Review |
| 8 | Discussion |
| 9 | EXAM I |
| 10 | Introduction: Neural polarity and Induction |
| 11 | Regionalization |
| 12 | Neurogenesis and Neuronal Migration |
| 13 | Neuronal Fate Specification |
| 14 | Axon Guidance |
| 15 | Synaptogenesis and Synaptic Pruning |
| 16 | Discussion/Student Presentations |
| 17 | Discussion/Student Presentations |
| 18 | Discussion/Student Presentations |
| 19 | EXAM II |
| 20 | Gene Structure and Function in the Nervous System |
| 21 | Neurogenetic I |
| 21 | Neurogenetic II |
| 22 | Post-Transactional Regulation of Gene Expression in the Nervous System I |
| 23 | Post-Transactional Regulation of Gene Expression in the Nervous System II |
| 24 | Genomic Approaches to Neurological Disorders |
| 25 | Discussion |
| 26 | Student Presentation I |
| 27 | Student Presentation II |
| 28 | Student Presentation III |