NEURBIO 237: Neurobiology of Brain Aging is taught every other year in Winter Quarter by Professor Carl Cotman.

Dr. Carl Cotman
Prerequisite: NEURBIO 209
Course Objective:
Outlines some of the significant changes that occur in the aging brain, with a special emphasis on risk factors and protective strategies that promote successful brain aging. Topics include changes in synaptic plasticity, neurotrophic factors, and molecular mechanisms in aging.
Sample Syllabus:
| # | Topic |
| 1 |
Introduction of Course and Goals. Survey of Student’s Goals |
| 2 |
What are the Basic Facts on Brain aging and Alzheimer’s Disease 2018 Alzheimer’s Disease Facts and Figures |
| 3 |
What are the Basic Facts on Brain aging and Alzheimer’s Disease 2018 Alzheimer’s Disease Facts and Figures |
| 4 | NIH and its Key Role in Sustaining the U.S. Economy/2018 Update |
| 5 | What are the Neuropathological Alteration in Alzheimer Disease |
| 6 | Principles of Good Experimental Design |
| 7 | Attend Research Seminar |
| 8 | How do Tangles Develop and Spread with Disease Progression? |
| 9 | Can Lifestyles Delay Onset of AD? |
| 10 | Discussion |
| 11 | What are the GWQS Genetic Risk Factors and What is Their Impact? |
| 12 | How does Physical Activity Protect the Aging Brain I |
| 13 | How does Physical Activity Protect the Aging Brain II |
| 14 | Discussions |
| 15 | What Does Physical Activity do for Brain Health? |
| 16 | Continued Discussion |
| 17 | What is the Microbiome and How is it Related to Brain Aging? |
| 18 | Class Discussion on HSV I |
| 19 | Class Discussion on HSV II |
| 20 | Can Immunization Protect the Brain from Beta-amyloid? |
| 21 | Invited Lecturer |
| 22 | Discussion of Mini Presentation by Students on Their Selected Topic |
| 23 | COntinued Discussion with Students on Their Papers |
| 24 | Class Presentation of Paper Topics |
| 25 | Class Finals |
