N152: Developmental Neurobiology is taught in the Fall Quarter by Professors Karina Cramer and Susana Cohen-Cory.
Dr. Karina Cramer
Dr. Susana Cohen-Cory
Prerequisite: BIO SCI 93
Course Objective:
The development of the nervous system is discussed with emphasis on the processes that underlie the appearance of complex and highly ordered neural circuits. Topics include neural induction, specification, migration and death; axon growth, and neural circuit formation.
Sample Syllabus:
| # | Topic |
| 1 | Model Organisms, Methods |
| 2 | Neural Induction |
| 3 | Regionalization |
| 4 | Neurogenesis and Gliogenesis |
| 5 | Neuronal Migration |
| 6 | Neuronal Fate Specification |
| 7 | Early Brain Development – Paper Discussion |
| 8 | Neuronal Cell Death |
| 9 | Review |
| 10 | MIDTERM EXAM |
| 11 | Axon Growth and Guidance I |
| 12 | Axon Growth and Guidance II |
| 13 | Target Selection |
| 14 | Axon and Dendritic Branching |
| 15 | Synapse Formation and Maturation I |
| 16 | Synapse Formation and Maturation II |
| 17 | Circuit Formation – Paper Discussion |
| 18 | Activity-Guided Synapse Formation |
| 19 | Sensory and Experience-Guided Neural Development |
| 20 | Review |
| 21 | FINAL EXAM |