N172: Regenerative Neurobiology is taught Winter Quarter by Professors Mathew Blurton-Jones and Sunil P. Gandhi.

matthewblurtonjones_100614_02_daa_a472x315 (from Chair Office)

Dr. Mathew Blurton-Jones

professor gandhi

Dr. Sunil P. Gandhi

Prerequisite: BIO SCI N110

Overlaps with BIO SCI 44, BIO SCI D133.

Course Objective:

This course will introduce students to the latest research on regenerative neurobiology. Both basic stem cell discoveries and their potential clinical application to brain disorders will be examined. The goal is to discuss the opportunities and pitfalls in the potential application of neural stem cells to brain repair. Lectures and in-depth discussions will build upon students’ strong understanding of neuroscience principles gained in previous course work.

Sample Syllabus:

# Topic
1 Course Overview
2 Quick Brain Tour
3 Critical Periods of Brain Development
4 Rewiring the Adult Brain
5 Neurogenesis in the Adult Brain
6 Stress and Neurogenesis
7 Exercise and Neurogenesis
8 Cell Suicide
9 Autism
10 Retinal Repair
11 Midterm Review
12 Brain Cell Replacement Strategies
13 Guest Lecture
14 Induced Pluripotent Stem Cells
15 Alzheimer’s Disease
16 Differentiation of Brain Cells
17 Cellular Optical Brain Interfaces
18 Stem Cells as Therapeutic Agents
19 Parkinson’s Disease
20 ALS and SMA
21 Immune Rejection
22 Rare Pediatric Disorders
23 Delivery Technology
24 Successes/Caveats for Clinical Translation
25 Ethics and Regulation of Stem Cell Research
26 Open Discussion
27 Final Review