Bio 44: Stem Cells and Brain Repair is taught in Winter Quarter by Professors Mathew Blurton-Jones and Sunil Gandhi.

matthewblurtonjones_100614_02_daa_a472x315 (from Chair Office)

Dr. Blurton-Jones

Overlaps with BIO SCI N172.

Course Objective:

This course will introduce students to the latest research on neural stem cells. We will examine both basic discoveries about neural stem cells and how these cells might be used to treat brain disorders. We will also discuss how new neurons are naturally generated in the brain. The goal is to clarify the opportunities and pitfalls for the most promising stem cell approaches to brain repair. The course will be relevant to those interested in this exciting new field of medical research as well as those concerned with the distinctive ethical and regulatory implications of regenerative medicine.

Sample Syllabus:

1Course Overview
2A Quick Tour of the Brain
3Critical Periods of Brain Development
4Rewiring the Adult Brain
5Neurogenesis in the Adult Brain
6Stress and Neurogenesis
7No Class – MLK Jr. Holiday
8Exercise and Neurogenesis
9Cell Suicide
11Retinal Repair
12Midterm Review
14TA Guest Lecture
15Brain Cell Replacement Strategies
16Induced Pluripotent Stem Cells
17Alzheimer’s Disease
18Differentiation of Brain Cells
19No Class – President’s Day Holiday
20ALS and SMA
21Cellular Optical Brain Interfaces
22Parkinson’s Disease
23Delivery Technology
24Rare Pediatric Disorders
25Immune Rejection
26Successes/Caveats or Clinical Translation
27Ethics and Regulation of Stem Cell Research
28The Stem Cell Research Investment Challenge
29Lab Tour (Meet at Gross Hall)