HomeUndergraduate ProgramsUpper Division CoursesN150: Neurodegeneration

N150: Neurodegeneration

N150: Neurodegeneration is taught in Spring Quarter by Professors Jorge Busciglio, Kim Green, and Leslie Thompson.

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Dr. Jorge Busciglio Dr. Kim Green Dr. Leslie Thompson


N150 is an upper division class aimed at Biological Sciences and Neurobiology Majors.  It requires N110 as a prerequisite course, and covers neurodegenerative diseases in a small classroom setting with an emphasis on discussion and group participation.  Throughout the course many neurodegenerative diseases will be covered, including Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, Down Syndrome, Frontotemporal Dementias, and damage due to injury to specific brain regions. In addition, students will learn about the techniques and technologies that allow us to study CNS disorders, as well as the possible current and future treatment options for these diseases.

No textbook is required, and class size is typically between 20-50 students.

Sample Syllabus:

Week 2 Intro to the brain

Modeling diseases in mice

Week 3 Alzheimer’s disease 1

Alzheimer’s disease 2

Week 4 Microglia and the Brain

Parkinson’s Disease

Week 5 Amyotrophic lateral sclerosis (ALS)


Week 6 Down’s syndrome

Traumatic Brain Injury and Stroke

Week 7 Stem Cell Transplantation


Week 8 Protein misfolding/clearance in neurodegen

Huntington’s disease

Week 9 Clinical Trials

Epigenetics in neurodegeneration

Week 10 Stem cell approaches for neurodegeneration

Axonal transport in neurodegeneration

Week 11 Mitochondria/Energy in neurodegeneration