N155: Wiring and the Brain is taught in Winter Quarter by Professor Susana Cohen-Cory.

S Cohen-Cory

Dr. Susana Cohen-Cory

Prerequisite: BIO SCI N110 or BIO SCI N152

Course Objective:

The development of the nervous system will be discussed with particular emphasis on the processes that underlie the appearance of complex and highly ordered neural circuits during embryonic development. Basic mechanisms of development will be analyzed and related to deficits that can lead to complex developmental disorders. Specific topics to be covered are: neuronal specification, neuronal migration, guidance of nerve processes to their targets, and the formation and maintenance of synaptic connections.

Sample Syllabus:

Week #Topic
1Course Organization and Introductory Lecture
2Neuronal Patterning
3No Class – MLK Holiday
4Neuronal Migration and Developmental Disorders
5Neuronal Migration and Developmental Disorders
6Growth Cones, Pathfinding Mechanisms, and Neural Circuit Formation
7No Class – President’s Day
8Dendrite Branching – Self Avoidance Mechanisms
9Synaptic Competition – Battle at the Neuromuscular Junction
10Synaptogenesis and Neurodevelopmental Disorders